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Anti-hTERT Antibody (SCD-A7)

Sienna Cancer Diagnostics have developed an assay to hTERT using the clone SCD-A7. This is the only IVD antibody for the detection of hTERT using immunocytochemistry. Available now, please contact sales@histocyte.com.

[HCL025]: Anti-hTERT Antibody 1ml

hTERT Expression
hTERT negative and positive cells

Telomerase is a ribonucleoprotein that adds repeats (TTAGGG) to the telomere ends, thus maintaining their integrity. The catalytic component of telomerase is known as the human telomerase reverse transcriptase (hTERT). By continually adding repetitive DNA sequences, the natural degradation of the chromosomal ends is prevented, thus enabling replication to carry on unchecked.
Identification of the presence of hTERT provides useful adjunct information to assist in making a diagnosis. hTERT is not expected to be detected in normal urothelial cells, so identification of this biomarker is very relevant. It is potentially useful in identifying increased potential for cancer when urine cytology is negative or atypical.